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[DOI] [PMC free article] [PubMed] [Google Scholar] 21.Gojkovic S., Krezic I., Vranes H., Zizek H., Drmic D., Vuletic L.B., Milavic M., Sikiric S., Stilinovic I., Simeon P., et al

Conservative recommendation: Manufacturers and clinics typically recommend 28-30 days because it balances safety (bacterial growth risk) with peptide stability

Methylcobalamin B12 is also indicated in those with pernicious anemia, diabetes, neuropathy, heart disease, circadian rhythm sleep disorders, memory loss, depression, fatigue, AIDS, inflammatory bowel disease (IBD), Lyme disease, osteoporosis, tendonitis, psychiatric disorders, Alzheimers disease, liver and kidney disease, and asthma

If you absolutely must use sterile water, you should plan to use the entire vial very, very quickly

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