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During the Telogen phase, that lasts for several months, the cell division stops, hair growth ceases, and the attachment of the hair to the base of the follicle becomes progressively weaker

9 Therefore, newer, more effective, and safer pharmacological interventions are needed to augment lifestyle interventions in overweight and obesity

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the second is that the long-term stimuli-increased secretory activity leads to a depletion of the releasable insulin of -cells 31