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Fig.2 Pleiotropic effects of GLP1-RA leading to improvement MASLD/MASH [2] GLP-1RA in MASH Treatment: Clinical Progress Several GLP-1RAs and related agents are currently in various phases of clinical development for MASH treatment [4]

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The blood sugar benefits are excellent, and the weight loss is a meaningful bonus that improves overall diabetes management

Expect early discomfort, financial commitment, and a shift in thinking about weight as a chronic condition rather than a temporary problem

With a more convenient oral formulation, Novo can position itself as a competitor to traditional diabetes medications, such as metformin, sulfonylureas, and SGLT2 inhibitors that are taken by mouth