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Neuroinflammation 9:201

The safety profile of BPC-157 and TB-500 in humans is not well characterized , because the controlled human trials that would establish safety, side-effect frequency, and long-term effects have not been conducted

Zhang Y, Xu J, Li R et al (2023) Plants response to abiotic stress: mechanisms and strategies

However, native amylin presents significant challenges for therapeutic use, including rapid enzymatic degradation, tendency to form pathological amyloid fibrils, and poor bioavailability when administered exogenously