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Certain factors may put you at increased risk for B12 deficiencyincluding a vegetarian or vegan diet, specific medical conditions (such as Crohns or celiac disease, or a history of gastric surgery), and age over 50

It takes one or two sessions every week for six months to achieve skin-lightening effects

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Research indicates it can normalize circadian melatonin production patterns that become dysregulated with aging, potentially through effects on pineal gene expression and enzyme activities involved in melatonin synthesis