Key Points Copper peptides especially GHK-Cu and AHK-Cu are short amino-acid chains bound to copper that activate hair follicle stem cells, extend the growth (anagen) phase, and trigger the Wnt/-catenin signaling pathway
18, 4 Sept
Genetic or pharmacological blockade of GIP, GLP-1, or PPAR signaling markedly reduced metabolic effects, supporting a combined incretinPPAR mechanism of action
doi: 10.3389/fncel.2024.1426231 Received 01 May 2024 Accepted 14 June 2024 Published 05 August 2024 Volume 18 - 2024 Edited by Wensheng Lin, University of Minnesota Twin Cities, United States Reviewed by Zhixin Lei, Wuhan University of Technology, China Carlos Matute, Achucarro Basque Center for Neuroscience, Spain Updates Copyright 2024 Stys, Tsutsui, Gafson, t Hart, Belachew and Geurts
doi: 10.3389/fcvm.2025.1661563 Received 21 July 2025 Accepted 09 October 2025 Published 29 October 2025 Volume 12 - 2025 Edited by Manuel Gmez-Guzmn, University of Granada, Spain Reviewed by Manuel Snchez Santos, University of Granada, Spain Javier Molen Moya, University of Mnster, Germany Updates Copyright 2025 Nzobokela, Muchaili, Mwambungu, Masenga and Kirabo