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Cell-free in vitro methods offer precision, high throughput and control to identify the direct interaction of a compound or extract with a specific molecular target (e.g., enzymes, receptors), being suitable for initial screening (59, 60)

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Before 2013s breakthrough clinical proof, it was understood that the bodys protection from toxicity was borne mainly by the liver, and that the depletion of glutathione contributed to that organs functional decline

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