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Type 2 diabetes can be challenging enough to manage without the added risk of chronic kidney disease, and I have seen in my own practice that patients with type 2 diabetes and chronic kidney disease need extra support from medications that may have a profound clinical impact by lowering the risk of major kidney and cardiovascular outcomes, said Richard E

These early safety and pharmacokinetic studies preceded Phase 2 dose-ranging work in 20042006 and the Phase 3 pivotal trials that began in 2006

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