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Investigation: SUK, JM, KH, JF, JK, SK, and AW

MDMA has been suggested as a treatment for: post-traumatic stress disorder (PTSD) disordered eating alcohol addiction and dependency anxiety in people with a terminal illness social anxiety in autistic adults co-occurring PTSD and opioid dependency When used in a therapeutic setting, MDMA may enhance many aspects of talk therapy

Another evidence linking the NAD + metabolism with DNA methylation is the NNMT, which transfers the methyl group from SAM to NAM, producing S-adenosylhomocysteine (SAH) and a stable metabolites 1-methylnicotinamide (MNA)

This supports overall bodily functions, can help manage appetite, and minimizes potential medication-related side effects like constipation

Sahebkar, 2011