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The clinically most important application of this knowledge has been the use of ablative or stimulation treatment applied to the basal ganglia motor circuit as treatment for hypo- and hyperkinetic disorders [44]

They are both particularly susceptible to oxidative stress due to the high percentage of oxygen required for healthy brain function

While direct evidence for Dihexa's effects on neurogenesis remains limited, the HGF/c-Met system that Dihexa activates is known to stimulate stem cell differentiation and promote neurogenesis in the adult hippocampus