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In recent years, with rising global temperatures, the incidence and mortality of heat stroke have increased significantly worldwide [7]

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In addition, ARNTL2 knockdown decreases N-cadherin expression and increases the expression of -catenin and E-cadherin in lung adenocarcinoma cells, while the opposite effects are observed in ARNTL2-overexpressed cells, 118 suggesting that ARNTL2 overexpression may promote EMT by inhibiting ferroptosis

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