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More research is needed, and long-term safety above 2g/day hasnt been firmly established

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Regional and cell-type differences are substantial, and observed changes may involve synthesis, transport, mitochondrial balance, or neuroinflammation (Aoyama, 2021)

Fluvastatin and lovastatin target the cholesterol pathway that plays a role in the prenylation of members of the PI3K/AKT/mTOR pathway and RAS, which could impact on the ability of RAS to activate BRAF [67], eventually causing a proliferation arrest