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Collagen, a vital protein responsible for skin elasticity and firmness, naturally diminishes over time, leading to sagging and wrinkles

This proposed activation of the GHRH receptor by Tesamorelin and the subsequent cAMP-PKA signaling cascade may stimulate the synthesis and secretion of growth hormone (hGH) from somatotrophs in the pituitary gland

Particularly, the effect of WS on GABA and serotonergic pathways may reduce the activation of the HPA axis, diminishing the secretion of corticotropin-releasing hormone and adrenocorticotropic hormone from the hypothalamus and pituitary, respectively, resulting in lower levels of cortisol released from the adrenal cortex [159]