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Glutathione in autism has become the topic of great interest as the scientists explore the theory that autism may be triggered by exposure to heavy metals, pesticides and other environmental toxins, coupled with a weak immune system and nutrient deficiencies in both mothers and children during fetal development and early life

doi: 10.1038/jid.2010.433

[23] Regulation [edit] Aside from deactivating radicals and reactive oxidants, glutathione participates in thiol protection and redox regulation of cellular thiol proteins under oxidative stress by protein S -glutathionylation, a redox-regulated post-translational thiol modification

Regarding membrane organization, 17 proteins were affected, including the down-regulation of EGFR (epidermal growth factor receptor) and AKT1 (protein kinase B) and the up-regulation of APOO (apolipoprotein O) and PACS1 (phosphofurin acidic cluster sorting protein-1) (Figure 5D)

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