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18(S10): p

Because L-Citrulline largely bypasses first-pass liver metabolism, it raises plasma L-Arginine levels more efficiently than direct L-Arginine supplementation, gram for gram - a pharmacokinetic advantage that's driven by growing research interest in this amino acid specifically

J Pharmacol Sci (2008) 106(2):1805

These findings further support the antioxidant role of GCLC and its ability to mitigate MPTP-induced glutathione depletion and neurotoxicity in Parkinsons disease models