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Many side effects are dose-related and will resolve when it is adjusted or at the end of therapy

Phase 3: Maintenance (Weeks 9+) Dose: 0.1 mL (10 units) subcutaneous, 2-3x weekly Pulsed administration keeps the repair signal present without turning the protocol into constant stimulation: Signal sensitivity pulsed dosing is the conservative way to avoid blunting the response over time

2013 Aug;36 Suppl 2(Suppl 2):S245-52