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In addition, the results of an in vitro permeation study on rat skin revealed that drug accumulation within the skin layers was approximately 3 times higher, while the drug flux into the receptor phase of Franz cells was about 6.5 times lower in hydroquinone-loaded SLNs in comparison to the hydroquinone gels which confirmed the reduced systemic absorption and further reduced adverse drug reactions through the encapsulation in SLNs (Wu et al., 2017)

Alongside its antioxidant power, glutathione protects the body in other ways

Acknowledgements This manuscript was funded by National Nature Science Foundation of China (No

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However, in a previous study carried out in Calu-3 cells, it was shown that exposure to cigarette smoke causes a decrease in the synthesis of CFTR mRNA, which was reflected in the expression of the protein [121]