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2022;102(5S):S1S127

Preclinical neuroprotection in cell and rodent models has a long history of failing to translate to human brain disease

In 2023, the Danish pharmaceutical company made an impressive $13.52 billion from Ozempic

and lateral, 0.3 mm from the bregma)

For a class of drugs already transforming millions of lives, this approach could further enhance both efficacy and tolerability, underscoring that responses to GLP-1 therapies are shaped not only by pharmacology but also by the subtle variations of the human genome