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In addition, the development of personalized treatment strategies based on individual patient profiles could amplify the efficacy of cancer therapeutics

Published in Neuroscience Gabrielle Ahern and 4 others Alzheimers disease (AD) is renowned as one of the most maleficent neurodegenerative disorders and is a major cause of dementia that slowly destroys the daily life of afflicted individuals

Although CFH appears to be a viable target for therapeutics, fourteen CFH inhibitors have been tested, with only three reaching phase III clinical trials

We reasoned that TBB might preferentially trigger apoptosis of senescent cells and investigated this hypothesis by using different concentrations of TBB to treat Zmpste24 -deficient MEFs and quantifying their apoptosis