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In some embodiments, formulations or compositions described herein comprise amorphous particles

Leave to air-dry for 30 seconds

The hard capsule may be filled with the lyophilizate powder of the composition of the present invention, or the lyophilizate powder of the present composition may be compressed to tablets for rectal administration or oral administration respectively

[DOI] [PMC free article] [PubMed] [Google Scholar] 33.Yates J.R., Sepp T., Matharu B.K., Khan J.C., Thurlby D.A., Shahid H., Clayton D.G., Hayward C., Morgan J., Wright A.F., et al

In both mice and rhesus macaques, a two-dose intramuscular immunization regimen resulted in durable, robust, and broad neutralization against all SARS-CoV-2 variants tested, including the Omicron subvariants BA.4/539 and BQ.140