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A second patient on commercial therapy with BardetBiedl syndrome, fair skin (Fitzpatrick skin type II), and a skin examination revealing extensive chronic UVrelated damage who lived on an island close to the equator experienced increased pigmentation of the skin and existing melanocytic nevi and was diagnosed with stage pT1a superficial spreading melanoma after 6 months of setmelanotide treatment

COA-verified copper peptide (GHK-Cu)

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Subsequently, it inhibited cell proliferation, promoted G0/G1 phase arrest and mitochondrial-dependent apoptosis via ERK1/2