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Structural diversity among agonist-bound states has been directly visualized by cryo-EM of GLP-1R in complex with multiple peptide agonists, confirming that conformational plasticity at the extracellular face propagates to the G protein interface in agonist-specific ways (Cary et al., 2021)

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Your healthcare provider can help you choose the injection site that is best for you o You may inject into your upper leg (front of the thighs), lower stomach (keep 2 inches away from your belly button) or upper arm

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