Partial degradation doesn't produce half-strength doses
At week 72, the percentage change in weight was -15.0% with 5 mg of tirzepatide, -19.5% with 10 mg, and -20.9% with 15 mg, compared to -3.1% with the placebo
Over time, this can lead to deficiencies in macronutrients (especially protein) and critical micronutrients including B-complex vitamins, calcium, magnesium, and iron - nutrients essential for neuromuscular, hematologic, and bone health
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