Glucagon-like peptide-1, or GLP-1, is a naturally occurring intestinal hormone involved in glucose regulation, appetite, and digestion
It also lowers blood sugar to prevent harmful effects of high blood sugar
Its extended shelf life post-opening makes it ideal for clinical environments requiring small dose adjustments over time
Individuals with type 1 diabetes, thyroid cancer, multiple endocrine neoplasia, or end stage kidney disease at any time until cohort entry or individuals with dialysis or the latest eGFR 70 years, by males versus females, by insulin use, by atherosclerotic cardiovascular disease (i.e., myocardial infraction, angina, coronary artery disease, coronary revascularization, peripheral artery disease, aortic atherosclerotic disease, or cerebrovascular disease), by renal insufficiency (i.e., chronic kidney disease or the latest eGFR 70 years (HR [95% CI]: 0.95 [0.831.08])
Many users find a Sunday-evening or Monday-morning injection routine works best, with the gentlest meals scheduled Monday and Tuesday
