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Saline is used far more broadly in healthcare than bacteriostatic water or sterile water alone beyond reconstitution, it's a common intravenous fluid for hydration and medication delivery, and it's also used as a wound cleanser

The cards below summarise the chemistry, the body's stockpile, and where each is found in the diet

Tierney et al., 2019)

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Additionally, there are indirect factors influencing TJs, such as matrix metalloproteinases (MMPs), NO, ROS, Rho-associated protein kinase (ROCK), and NF-B signaling pathways [120,121,122,123,124]