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L-Phenylalanine An amino acid involved in appetite signalling and satiety, helping support feelings of fullness

Common adverse reactions in TRESIBA treated pediatric patients with type 1 diabetes mellitus were similar to the adverse reactions listed in Table 1

The total weight loss by 3 months averages 510% of starting body weight in clinical studies, with continued loss possible over 612 months with dose optimization

In February 2026, Lilly also introduced multi-dose KwikPen devices through LillyDirect at $299 to $449 per month

Those who experience side effects report queasiness or nausea, with a very small percentage reporting vomiting, diarrhea, or constipation