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GSH is synthesiszed via two ATP-dependent processes that are catalysed by -Glu-Cys synthetase (GSH1) and GSH synthetase (GSH2), and it is mostly degraded by -Glutamyl transpeptidases (-GT), which split GSH into cysteinyl-glycine (Cys-Gly) and Glu residue
Patients who judge their progress entirely by the scan numbers at week 12 often conclude the treatment is not working
This study population was then divided into two cohorts: (1) Semaglutide cohort 688 patients prescribed semaglutide, and (2) non-GLP1-RA anti-obesity medication cohort 1,346 patients prescribed non-GLP-1RA anti-obesity medications but not semaglutide
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