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This powerful tripeptidea small protein made of three amino acidsis produced in nearly every cell you have

While it shares structural similarities with GHK-CU, the single amino acid difference produces notably different biological effects

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Given the importance of GRK levels to morphine-dependent regulation of receptors in model cell systems, it is conceivable that alterations in GRK2 expression or subcellular distribution following chronic opioid treatment could contribute to significant reprogramming of opioid regulatory responses

Yankner BA, Dawes LR, Fisher S, Villa-Komaroff L, Oster-Granite ML, et al