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Persistent itch that lasts more than 24 hours after each use suggests you might be sensitive to one of the actives

Epithalon is for research purposes only and is not intended for human or animal use, diagnosis, treatment, or consumption

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In a long-term randomized, double-blind, placebo-controlled study among sufferers of cerebrovascular accidents at high risk of depression, daily supplementation with 2 mg of folic acid, 25 mg of vitamin B6, and 500 g vitamin B 12 significantly lowered the risk of major depressive episodes during a seven-year follow-up period compared to placebo (111)