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PMID: 22459616

If you have diabetes and take insulin or sulfonylureas, monitor your blood glucose levels carefully when reducing carbohydrate intake, as dose adjustments may be needed to prevent hypoglycaemia

Potentiation of the glycine response by bisphenol A, an endocrine disruptor, on the substantia gelatinosa neurons of the trigeminal subnucleus caudalis in mice

Structural Characteristics PT-141 shares the core cyclic lactam heptapeptide scaffold of MT-2cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NHwith a single structural distinction: the N-terminal norleucine residue carries a free amine (H-Nle-) rather than the acetyl cap (Ac-Nle-) present in MT-2