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A 12-week clinical trial showed subjects taking AOD-9604 (1 mg/d) lost an average of 2.6 kg, compared to 0.8 kg in the placebo group.

Mazzali G, Di Francesco V, Zoico E, Fantin F, Zamboni G, Benati C, et al

B12 is of particular concern for anyone reducing animal protein consumption, as it is found almost exclusively in animal-sourced foods

Clinicians should maintain a high index of suspicion for alternative diagnoses and investigate appropriately when patients report persistent or severe upper gastrointestinal symptoms

[DOI] [PubMed] [Google Scholar] 132.Guerrero-Hreins E, Goldstone AP, Brown RM, Sumithran P