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Thomas FC, Taskar K, Rudraraju V, Goda S, Thorsheim HR, Gaasch JA, Mittapalli RK, Palmieri D, Steeg PS et al (2009) Uptake of ANG1005, a novel paclitaxel derivative, through the blood-brain barrier into brain and experimental brain metastases of breast cancer

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Requires close monitoring and structured dietary support to avoid excessive deficit

When combining the two, expect nausea to be most pronounced during dose escalation periods, particularly when both compounds are being increased in close succession