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Furthermore, pathological alteration of gastrointestinal flora may lead to diseases, such as inflammatory bowel disease and cancer

That compares with a weight loss of 2.3% for people who received a placebo

The most common clinical cause for concern about a pigmented lesion is a reported changing mole. In an otherwise previously uniform symmetric nevus, such changes typically include an increase in size, the formation of irregular borders with adjacent normal skin, and a peripheral change in color