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The SELECT cardiovascular outcomes trial demonstrated a 20 percent reduction in major cardiovascular events, suggesting benefits beyond weight loss that may justify long-term use even after weight goals are achieved

Important things to consider for the rate of administration include: Watching the patients vital signs Changing the rate based on how the patient reacts Not giving it too fast to prevent bad reactions Emergency Protocols for Severe Deficiency For severe Vitamin B12 deficiency with neurological symptoms or severe anemia, emergency steps are needed

However, clinical trials in humans have demonstrated mixed results

Most people report feeling the effects of mobile B12 for as long as two weeks following the injection

Half-life: AOD-9604 approximately 4 minutes (preclinical estimate)