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As such, further studies should explore whether the beneficial effects observed in PsO and early PsA could be replicated in other autoimmune disorders, providing broader therapeutic benefits across this category of diseases

However, genetic variants in GLP-1 receptor (GLP1R) and glucose-dependent insulinotropic polypeptide receptor (GIPR) genes influence how strongly an individual's gut responds to these medications, explaining why some tolerate them better than others

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