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(Also known as/Synonyms) Melanotic Macules of Mouth Melanotic Macules of Oral Cavity Oral Melanosis What is Melanotic Macules of Oral Mucosa

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Key Points Using expired semaglutide (Ozempic or Wegovy) is not recommended due to reduced effectiveness and potential safety risks Semaglutide is stable for 36 months when refrigerated unopened, but only 6-8 weeks after first use Unlike many medications, biologics like semaglutide can lose potency quickly after expiration Expired semaglutide may not control blood sugar or support weight loss as effectively due to dose-dependent benefits Found an old Ozempic or Wegovy pen in your fridge

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It could be further confirmed that it is the MSU crystals that cause the release of IL-1 by activating the NLRP3 inflammasome, which is consistent with our previous findings in human monocytes