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Journal of Herpetology , 44/3: 390-398
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The medication is produced using recombinant DNA technology in yeast cells ( Saccharomyces cerevisiae ), a well-established pharmaceutical manufacturing method also used for insulin and other biologics
This study was supported by the Special Coordination Funds for Promoting Science and Technology, Creation of Innovation Centers for Advanced Interdisciplinary Research Areas (Innovative Bioproduction Kobe), MEXT, Japan
Furthermore, the dual effects of BEZ235 on PI3K/Akt and mTOR signaling pathways inhibit the activation of fibroblasts and eliminate the defect of rapamycin in p-Akt feedback activation of Ser473 after treatment with TGF- [131]
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