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GPCR endocytosis is in many cases dependent on the recruitment of -arrestins, which interact with clathrin adaptors to promote internalization via clathrin-coated pits 33

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It's metabolized and cleared by the kidneys, and while preclinical data shows promise for kidney recovery, comprehensive human safety isn't established

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The GM serves as a major source of several vitamins, including B vitamins and vitamin K (193)