In addition, L-2-HG accumulation in an acidic pH environment has been reported to result in HIF-1 stabilization in normoxia 91 (Fig
A phase 2 multicenter, open-label, randomized, controlled trial in patients with stage II/III colorectal cancer who are ctDNA positive following resection to compare efficacy of autogene cevumeran versus watchful waiting
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10.3389/fcell.2025.1619758 [DOI] [PMC free article] [PubMed] [Google Scholar] Colella M., Cuomo D., Peluso T., Falanga I., Mallardo M., De Felice M., et al
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