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Instead of universal withholding, the guidance emphasized shared decision-making and targeted risk reduction for patients most likely to have delayed gastric emptying, such as those in the dose-escalation phase, those with notable gastrointestinal symptoms, those on higher doses, and those with comorbid conditions that slow gastric emptying

[DOI] [PubMed] [Google Scholar] 19.Evans D.G., OHara C., Wilding A., Ingham S.L., Howard E., Dawson J., Moran A., Scott-Kitching V., Holt F., Huson S.M

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For example, the antidiabetic drug metformin affects traits or adaptations that make bacterial strains resistant to aminoglycosides [123]