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In summary, MAT, Dabrafenib, bone marrow mesenchymal stem cell-derived exosomes miR-367-3p, and DFP modulate ferroptosis, iron deposition, lipid peroxidation, neuroinflammation, microglial activation, and myelin loss, thereby attenuating MS-related pathological damage

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The doublet of gedatolisib and fulvestrant achieved 7.4 months median PFS, a 67% risk reduction

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