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The guide on whether semaglutide increases estrogen levels covers a related hormonal consideration that some people on semaglutide ask about in the context of endocrine monitoring

GLP-1 users also suffered 28.7 incidents of acute kidney injury per 100 individuals after five years, compared to 25.2 per 100 among SGLT2 users

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Tirzepatide did not increase risks of adverse renal events, urinary tract infections, nephrolithiasis (kidney stones), acute kidney injury, or renal cancer compared to placebo, insulin, or other GLP-1 receptor agonists

However, be cautious about over-supplementing, as too much of any mineral can cause its own problems