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17 Alternatively, surgery to remove the prolactin-secreting tumor (a non-cancerous tumor in the pituitary gland) has also been shown to successfully lead to remission

Some patients respond exceptionally well to GLP-1 monotherapy, while others may need the additional mechanisms of dual or triple agonists

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Velasco J

Efficacy Context: Clinical trials for combination therapies like naltrexone-bupropion or phentermine-topiramate typically show weight loss in the range of 510%, compared to 15% or more often seen with semaglutide in similar timeframes (Liu et al., 2024)