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While generally mild and self-limiting, persistent diarrhea warrants medical attention to prevent dehydration and assess for other potential causes

This sounds like a mouthful, but its not as complicated as you think: The forkhead box O family of proteins consists of 4 transcription factors that share a highly conserved DNA-binding, the forkhead box domain (FH)

Advances in high-resolution technologies such as single-cell omics, spatial metabolomics, and imaging mass spectrometry have progressively unveiled the metabolic heterogeneity landscape within CRC [130, 131]

Dose adjustments of these medications are typically necessary

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