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One such class of medications is GLP-1 receptor agonists, commonly prescribed for type 2 diabetes and weight management

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Wegovy works by affecting hormones that regulate appetite, and its benefits often decrease once the medication is discontinued

An expression construct encoding a human FLAG-tagged GLP-1R in pcDNA3.1, along with a hygromycin-resistant gene, was created by FLAG for subcloning a PCR product-tagged human GLP-1R into a cytomegalovirus promoter vector

Synaptogenesis & dendritic spines Investigated in rodent tissue and cell models for its reported ability to increase dendritic spine density preclinical only, and the primary source assays were retracted in 2025