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If your family history includes medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia type 2 (MEN2), GLP-1 therapy is contraindicated because these medications stimulate thyroid C-cells, raising cancer risk

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The first week often brings subtle changes, while weeks 2-4 typically show stronger appetite suppression

To evaluate the functional significance of these spine changes Nlel-AnglV and Dihexa stimulated hippocampal neurons were immunostained against the glutamatergic presynaptic marker VGLUT1 (Balschun, Moechars et al