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That decline doesnt equal gone. Nutrients can shift from circulation into muscles, nerves, or the liver, where they remain available beyond the blood window

Genetic background substantially influences the rate of bone loss in PMO, and bone resorption during PMO is strongly heritable (191)

The peak location is unknown in humans

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doi: 10.3389/fcell.2020.624477 Received 31 October 2020 Accepted 23 December 2020 Published 22 January 2021 Volume 8 - 2020 Edited by Silvia Brunelli, University of Milano-Bicocca, Italy Reviewed by Annarita Miccio, INSERM U1163 Institut Imagine, France