The glial-lymphatic system, also called the glymphatic system, works with the meningeal lymphatic vasculature to improve cerebral drainage
NR treatment increased cerebral NAD + levels and NAD + metabolome in CSF, skeletal muscle, and PBMCs
First principles for therapy design Therapy design should follow three first principles: target the source before the sink, prioritizing isoform- or site-specific modulation of NOX enzymes, mitochondrial ROS sites, ER oxidoreductases, or iron handling rather than indiscriminate scavenging that can blunt physiological signalling (Sies et al
3 If initial therapy with metformin and lifestyle efforts are not adequate to achieve individualized glycemic targets, the guidelines recommend that patients should progress to dual therapy by adding either another oral agent, basal insulin, or an injectable GLP-1 receptor agonist
BPC-157: A Healing Peptide BPC-157 may help reduce inflammation in the prostate and promote healing of damaged tissues, making it a promising addition to prostate health research
