However, it doesnt work in the same way as approved weight loss treatments like glucagon-like peptide-1 agonists (or GLP-1 injections)
10.2337/dc06-1373 31 BankirL.BoubyN.BlondeauB.CrambertG
pharmacological inhibition of NNMT has therefore become a major focus in laboratory research on adipose-tissue energy balance, methyl-donor recycling, and metabolic resilience
Uncoupling protein (UCP)-1 has been shown to be activated in HIV-associated lipodystrophy and in agreement, calcyphosine-like (CAPSL), important in early adipogenesis, was down-regulated and uncoupling protein (UCP)-1 upregulated in eleven individuals, one with familial MSL and ten with sporadic MSL disease (276)
Zhou R, Xu Q, Zheng P, Yan L, Zheng J, Dai G