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For example, as weight decreases, obstructive sleep apnoea often improves, which can change sleep quality and architecture

Superimposing the TMD of GLP-2R with that of GLP-1R reveals that activated GLP-2R shows a similar conformation to that of GLP-1-bound or ExP5-bound GLP-1RG s complexes 13,17 (C RMSD = 1.41 and 0.91 , respectively), distinct from inactive GLP-1R 33 (C RMSD = 1.79 )

Laakso ML, Hatonen T, Stenberg D, Alila A, Smith S

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Luo Y, Yang S, Zeng H, Liu S, Zhang Y, Li JE, Liu J (2025) Both subcutaneous semaglutide and calorie restriction improves pancreatic cell hyperplasia and gut microbiota in high-fat diet-induced obese mice